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KMID : 0359819950240060617
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Journal of Korean Neurosurgical Society
1995 Volume.24 No. 6 p.617 ~ p.622
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A Study of AgNORs(Argyrophilic Nucleolar Organizer Regions) on Prediction of the Prognosis on Intracranial Meningiomas
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Abstract
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A silver staining technique was used in the study of nucleolar organizer regions (AgNORs) from the paraffin sections of 26 meningiomas. The specimens were divided into four groups as follows : benign (n=16), atypical (n=5), anaplastic or
malignant
(n=5)
and recurrent without atypical histological findings (n=2) groups, and the mean number of AgNORs in each group was 1.47±0.27, 1.93±0.24, 2.00±0.27 and 1.49±0.53 respectively. We noted that the mean number of AgNORs reflected the cellular
kinetics of
a tumor and was related to histological grade. There was no significant difference between non-recurrent & recurrent benign meningiomas and it was thought that the main cause of recurrence in benign meningiomas was not perhaps cell proliferation
but
incomplete surgical removal.
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KEYWORD
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